RAMB4, CAS 145888-79-5

Formulation: A solid

Formal Name: 3,5-bis[(3,4-dichlorophenyl)methylene]-4-piperidinone

Purity: ≥98%

Formula Markup: C19H13Cl4NO

Formula Weight: 413,1

Shelf life (days): 1460

CAS Number: 145888-79-5

Notes: RAMB4 is an inhibitor of the ubiquitin-proteasome system.{68167} It increases the levels of polyubiquitinated proteins in HeLa cervical cancer cells, but does not inhibit the chymotrypsin-like, trypsin-like, or peptidylglutamyl peptide hydrolyzing-like activities of the 20S proteasome, in cell-free assays when used at a concentration of 10 µM. RAMB4 decreases the viability of HeLa cells (IC50 = 2 µM).

• SKU: CAY36936-250
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36936-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK
• Application: Reinstoffe