Rapamycin , CAS 53123-88-9

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CAS Number: 53123-88-9

Description: Immunosuppressant, related to FK-506, but without calcineurin inhibitory activity even when complexed to FK-506 binding protein. Selectively blocks signaling that leads to p70 S6 kinase activation (IC50 = 50 pM).

Format: Off-white or yellow solid.

Purity: ≥99%

Solubility: Soluble in DMSO at 200 mg/ml; soluble in ethanol at 50 mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM.

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Biosafety Level: Not applicable (BSL-1)

References: Terada, N., et al. J. Biol. Chem. 268: 12062-12068 (1993).

• SKU: BPS27062
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 27062
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK