Product Type: Inhibitor
CAS No.: 161735-79-1
MolecularFormula: C12H13N • CH3SO3H
Molecular Weight: 267,3
Source: Synthetic
Purity: >99% (HPLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml); Ethanol (30 mg/ml)
Appearance: White crystalline powder
PubChem CID: 3052775
Scientific Background: Rasagiline mesylate is an effective therapeutic in the early stages of Parkinon's Disease as it prevents the breakdown of dopamine by irreversibly binding to MAO-B. It has neuroprotective effects and increases the survival of dopaminergic neurons (1). It prevents alpha synculein induced dopaminergic meuronal death and rescues TrkB neurotrophic signaling (2).
References: 1. Stocchi F., Fossati C1, Torti M. (2015) Expert Opin Pharamcorther. 16(14): 2231-2241. 2. Chau KY., Cooper JM., Schapire AHV. (2010) Neurochem Int. 57(5): 525-529.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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