Rasagiline mesylate, CAS 161735-79-1

MAO inhibitor
SKU
STRSIH-577-50MG
Packaging Unit
50 mg
Manufacturer
Stressmarq Biosciences

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Product Type: Inhibitor

CAS No.: 161735-79-1

MolecularFormula: C12H13N • CH3SO3H

Molecular Weight: 267,3

Source: Synthetic

Purity: >99% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml); Ethanol (30 mg/ml)

Appearance: White crystalline powder

PubChem CID: 3052775

Scientific Background: Potent, irreversible monoamine oxidase (MAO) inhibitor selective for MAO-B (IC50=4.43 nM) over MAO-A (IC50=412 nM) (1). Parkinson’s disease therapeutic (2). Displays neuroprotective and neurorestorative properties in a Parkinson’s disease zebrafish model (3). Prevents α-synuclein-induced dopaminergic neuronal death and rescues TrkB neurotrophic signaling (4). Enhances BDNF levels and is neuroprotective in Parkinson’s disease models (5).

References: 1.MBH Youdim et al. Br. J. Pharmacol. 2001 132:5002.E Cereda et al. J. Neurol. 2017 264:12543.A Cronin and M Grealy Neuroscience 2017 367:344.SS Kang et al. Proc. Natl. Acad. Sci. USA 2017 114:107735.A Ledreux et al. Brain Res. 2016 1631:34

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
More Information
SKU STRSIH-577-50MG
Manufacturer Stressmarq Biosciences
Manufacturer SKU SIH-577-50MG
Package Unit 50 mg
Quantity Unit STK
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