Clone Number: A5
Immunogen: laminin preparation from murine EHS cells
Concentration: 100 ug/ml
Storage buffer: PBS with 0.02% sodium azide
Additional info: Laminins are large hetero-trimeric, non-collagenous glycoproteins found in basement membranes and composed of α, β, and γ chains. A5 reacts specifically with γ chain 1. Alterations of basement membrane integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
References: Ljubimov JY et. al. Cancer Res. 61(14): 5601-5610 (2001)/Ljubimov AV et. al. Int J Cancer 50: 562-566 (1992)/Ljubimov AV et. al. Lab Invest 72: 461-473 (1995)