Rat anti-MRP6 (ABCC6), clone M6II-7 (Monoclonal)

Clone Number: M6II-7

Immunogen: ABCC6 aa 764-964

Concentration: 250 ug/ ml

Storage buffer: supernatant with 1% BSA and 0.1% sodium azide

Additional info: M6II-7 reacts with MRP6, a 190-200 kD transmembrane protein that is related to the multidrug resistance related protein MRP. Mutations in the MRP6 gene are responsible for the connective tissue disorder Pseudoxanthoma elasticum (PXE). M6II-7 was raised against a bacterial fusion protein of human MRP6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein. M6II-7 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products. unreactive on standard IHC-P.

References: Bergen AA et al. Nat Genet 2000; 25: 228-231/Scheffer GL et al. Lab Invest 2002; 82: 515-518

• SKU: SANMON9047
• Manufacturer: Sanbio / Monosan
• Manufacturer SKU: MON9047
• Package Unit: 1 ml
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (frozen), Western Blotting, Flow Cytometry, Immunocytochemistry
• Isotype: IgG2a
• Host: Rat
• Conjugate: Unconjugated