Clone Name: 13A10
Application Note: WB: 1:25–1:50. IHC-P: 1:25–1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 106
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Uniprot ID: P06400
Antigen Species: Human
Immunogen: Recombinant prokaryotic protein corresponding to a portion of the N-terminal region of the retinoblastoma gene product.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: RB transcriptional corepressor 1
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