RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-1), 1mg/mL

RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9(CPTC-EBAG9-1), 1mg/mL
SKU
BTMBNUM2263-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: CPTC-EBAG9-1

Entrez Gene ID: 9166

Immunogen: Recombinant human full-length EBAG9 protein

Verified AB Applications: IF (verified)/IHC (FFPE) (verified)

Z-Antibody Applications: IF (verified)/IHC, FFPE (verified)
More Information
SKU BTMBNUM2263-50
Manufacturer Biotium
Manufacturer SKU BNUM2263-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunofluorescence, Immunohistochemistry
Isotype IgG2c kappa
Host Mouse
Conjugate Unconjugated
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