Recombinant Human 4-1BB/CD137 protein (His tag)

Abbreviation: 4-1BB;CD137

Target Synonym: CD137;ILA;TNFRSF9;4-1BB ligand receptor;CDw137;T-cell antigen 4-1BB homolog;T-cell antigen ILA

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: Q07011

Background: Tumor necrosis factor receptor superfamily member 9(TNFRSF9); also known as CD137 and 4-1BB; is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells; including endothelial cells; chondrocytes; and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system; is broadly expressed by cells of the human immune system; including activated CD8+ and CD4+ T cells; activated natural killer (NK) cells; follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response; the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).

Sequence: Met1-Gln186

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDMH100148-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100148-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK