Abbreviation: AIMP2
Target Synonym: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2;AIMP2;Multisynthase complex auxiliary component p38;Protein JTV-1
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q13155
Background: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Sequence: Met 1-Lys 320
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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