Abbreviation: AQP-3
Target Synonym: AQP 3;AQP-3;Aqp3;AQP3;Aquaglyceroporin-3;Aquaporin 3;Aquaporin-3;Aquaporin3;GIL;Gill blood group
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-GST
UNIProt ID: Q92482
Background: Water channel required to promote glycerol permeability and water transport across cell membranes.Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Sequence: Leu 110-Ser 170
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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