Recombinant Human BMP-2 Protein(Gst Tag)

Protein Tag: N-Gst

Uniprot: P12643

Accession: P12643

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Bio Acitivity: Not validated for activity

Sequence: Gln283-Arg396

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 38 kDa

Observed MW: 42 kDa

• SKU: ELSPDEH100524-500
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDEH100524-500
• Package Unit: 500μg
• Quantity Unit: STK
• Reactivity: Human
• Host: Escherichia Coli