Target Synonym: Butyrophilin subfamily 3 member A3;BTN3A3;BTF3;BTN3.3
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: O00478
Background: Human BTN3A3; also known as butyrophilin subfamily 3 member A3 and BTF3; is a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily and BTN/MOG family. The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin domains and an intracellular B30.2 (PRYSPRY) domain. It can be detected in peripheral blood mononuclear cells; T-cells l; spleen and lymphocytes. BTN3A3 plays a role in T-cell responses in the adaptive immune response.
Sequence: Gln30-Trp248
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.