Recombinant Human CASP9 Protein(Sumo Tag)

Protein Tag: N-Sumo

Uniprot: P55211

Accession: P55211

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Bio Acitivity: Not validated for activity

Sequence: Val139-Asp330

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method

Calculated MW: 36.4 kDa

Observed MW: 37 kDa

• SKU: ELSPDEH100514-500
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDEH100514-500
• Package Unit: 500μg
• Quantity Unit: STK
• Reactivity: Human
• Host: Escherichia Coli