Recombinant Human CD47/IAP Protein (mFc Tag)

Abbreviation: CD47;IAP

Target Synonym: Leukocyte surface antigen CD47;Antigenic surface determinant protein OA3;Integrin-associated protein;IAP;Protein MER6;CD47;MER6

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-mFc

UNIProt ID: Q08722

Background: CD47(Integrin-AssociatedProtein;IAP)is a 40?60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages; neutrophils; and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin; and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution; and is reduced in expression on Rh erythrocytes.

Sequence: Gln19-Pro139

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.

• SKU: ELSPDMH100022-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100022-100
• Package Unit: 100 µg
• Quantity Unit: STK