Recombinant Human CD5L/hAIM protein (His tag)

Abbreviation: CD5L;hAIM

Target Synonym: CD5 antigen-like;Apoptosis inhibitor expressed by macrophages;hAIM;CT-2;IgM-associated peptide;SP-alpha;CD5L;API6;UNQ203/PRO229

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: O43866

Background: CD5 Antigen-Like (CD5L) is a soluble protein that belongs to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. CD5L is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues. It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram-negative bacteria and the SRCR domain one of CD5L retains both the LPS and LTA binding activities. Furthermore, CD5L seems to play a role as an inhibitor of apoptosis.

Sequence: Met1-Gly347

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDMH100080-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100080-20
• Package Unit: 20 µg
• Quantity Unit: STK