Recombinant Human CFHR1 protein (His tag)

Abbreviation: CFHR1

Target Synonym: Complement Factor H-Related Protein 1;FHR-1;H Factor-Like Protein 1;H-Factor-Like 1;H36;CFHR1;CFHL;CFHL1;CFHL1P;CFHR1P;FHR1;HFL1;HFL2

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: Q03591

Background: Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H; the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains; termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five; approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation; lipid metabolism and lipoprotein complexes that bind PMNs to LPS.

Sequence: Thr205-Lys329

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100161-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100161-100
• Package Unit: 100 µg
• Quantity Unit: STK