Recombinant Human DRP1 protein (His tag)

Abbreviation: DRP1

Target Synonym: Dynamin-1-like protein;DNM1L;Dnm1p/Vps1p-like protein (DVLP);Dynamin family member proline-rich carboxyl-terminal domain less (Dymple);Dynamin-like protein

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: O00429

Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport.

Sequence: Asn 448-Trp 736

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100411-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100411-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK