Recombinant Human IGFBP3 protein(His tag)

Abbreviation: IGFBP3

Target Synonym: IBP-3;IGF-binding protein 3;IGFBP-3

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: P17936

Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity.Promotes testicular germ cell apoptosis.

Sequence: Met1-Lys291

Purity: > 80 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDMH100044-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100044-20
• Package Unit: 20 µg
• Quantity Unit: STK