Description: IL-5 functions as a growth factor in hematopoiesis, fostering the proliferation and activation of eosinophils. Its production primarily stems from mast cells, T cells, and eosinophils themselves. IL-5 plays a pivotal role in bolstering cell-mediated immunity against parasitic infections and specific tumors. Elevated IL-5 levels correlate with eosinophilia, a condition associated with the onset of asthma and other allergic disorders. Notably, both human and murine IL-5 exhibit cross-species reactivity. Recombinant Human IL-5 constitutes a 26.5 kDa disulfide-linked homodimeric protein, comprised of two 116 amino acid chains.
Expression System: E. coli
Molecular Weight: 26.5 kDa
Class: Recombinant
Endotoxin Concentration: <1 EU/µg
Activity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 10^6 units/mg.
Form: Lyophilized
Contains: no preservative
Storage Conditions: -20°C
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Caution: For Research Use Only. Not for use in diagnostic procedures.
Gene Symbol: IL5
Protein ID: P05113
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