Recombinant Human IL-7 Protein(Sumo Tag)

Protein Tag: N-Sumo

Uniprot: P13232

Accession: P13232

Background: IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.

Bio Acitivity: Not validated for activity

Sequence: Asp26-His177

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 32.6 kDa

Observed MW: 35 kDa

• SKU: ELSPDEH100516-500
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: PDEH100516-500
• Package Unit: 500μg
• Quantity Unit: STK
• Reactivity: Human
• Host: Escherichia Coli