Abbreviation: LDHA
Target Synonym: L-Lactate Dehydrogenase A Chain;LDH-A;Cell Proliferation-Inducing Gene 19 Protein;LDH Muscle Subunit;LDH-M;Renal Carcinoma Antigen NY-REN-59;LDHA
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P00338
Background: L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
Sequence: Ala 2-Phe 332
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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