Recombinant Human MCM3 protein (His tag)

Abbreviation: MCM3

Target Synonym: MCM3;P1 Protein;P1-MCM3;P1.h;p102;P102 protein;MCM 3;mcm3

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: P25205

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Sequence: Ser 41-Ala 300

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100142-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100142-100
• Package Unit: 100 µg
• Quantity Unit: STK