Recombinant Human MeCP2 protein(His tag)

Abbreviation: MeCP2

Target Synonym: MeCp-2 protein

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P51608

Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

Sequence: Met1-Lys177

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100115-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100115-100
• Package Unit: 100 µg
• Quantity Unit: STK