Recombinant Human NEDD8 protein (His tag)

Abbreviation: NEDD8

Target Synonym: Neural precursor cell expressed developmentally down-regulated protein 8;NEDD8;Neddylin;Ubiquitin-like protein Nedd8

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-10His

UNIProt ID: Q15843

Background: Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.

Sequence: Met 1-Gly 76

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100239-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100239-20
• Package Unit: 20 µg
• Quantity Unit: STK