Recombinant Human NKp30/NCR3 protein (His tag)

Abbreviation: NKp30;NCR3

Target Synonym: Natural Cytotoxicity Triggering Receptor 3;Activating Natural Killer Receptor p30;Natural Killer Cell p30-Related Protein;NK-p30;NKp30;CD337;NCR3;1C7;LY117;1C7;DAAP-90L16.3;MALS

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: O14931

Background: Natural Cytotoxicity Triggering Receptor 3; NCR3; also known as NKp30; or CD337; is a natural cytotoxicity receptor; expressed on subsets of human peripheral blood NK cells; involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive; but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity; and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.

Sequence: Met1-Gly135

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDMH100134-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100134-100
• Package Unit: 100 µg
• Quantity Unit: STK