Abbreviation: NOTCH3
Target Synonym: Neurogenic locus notch homolog protein 3;NOTCH3
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q9UM47
Background: Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes . The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. In both vertebrates and invertebrates, Notch signaling is important for specifying cell fates and for defining boundaries between different cell types.
Sequence: Val 1289-Cys 1458
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
English
Deutsch
