Recombinant Human PACT protein (His tag)

Abbreviation: PACT

Target Synonym: Interferon-inducible double-stranded RNA-dependent protein kinase activator A;PRKRA;PKR-associated protein X

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: O75569

Background: Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.

Sequence: Met 1-Lys 313

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100367-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100367-100
• Package Unit: 100 µg
• Quantity Unit: STK