Recombinant Human PD-L2/CD273 Protein (His Tag)

Abbreviation: PD-L2;CD273

Target Synonym: Programmed Cell Death 1 Ligand 2;PD-1 Ligand 2;PD-L2;PDCD1 Ligand 2;Programmed Death Ligand 2;Butyrophilin B7-DC;B7-DC;CD273;PDCD1LG2;B7DC;CD273;PDCD1L2;PDL2

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: Q9BQ51

Background: Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Sequence: Leu20-Pro219

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.

• SKU: ELSPDMH100020-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDMH100020-20
• Package Unit: 20 µg
• Quantity Unit: STK