Abbreviation: POSTN
Target Synonym: Fasciclin-I like;MGC119510;MGC119511;OSF 2;OSF-2;OSF2;Osteoblast specific factor 2 (fasciclin I like);Osteoblast specific factor 2;Osteoblast specific factor;Osteoblast-specific factor 2;PDLPOSTN;Periodontal ligament specific periostin;Periostin;Periostin isoform thy2;Periostin isoform thy4;Periostin isoform thy6;Periostin isoform thy8;Periostin osteoblast specific factor;PN;POSTN;POSTN;RP11 412K4.1
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q15063
Background: Periostin (POSTN,PN),originally named as osteoblast-specific factor 2 (OSF-2),is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.
Sequence: Ala21-Leu365
Purity: > 85 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 20mM Tris,1mM EDTA, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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