Abbreviation: PPAR-delta
Target Synonym: Peroxisome proliferator-activated receptor delta;PPAR-delta;NUCI;Nuclear hormone receptor 1;NUC1;Nuclear receptor subfamily 1 group C member 2;Peroxisome proliferator-activated receptor beta;PPAR-beta;NR1C2;PPARB
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q03181
Background: Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues.Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand
Sequence: Leu260-Glu426
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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