Recombinant Human Rad51 protein (His tag)

Abbreviation: Rad51

Target Synonym: DNA repair protein RAD51 homolog 1;RAD51;HsRAD51;hRAD51

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: Q06609

Background: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

Sequence: Ala 2-Asp 339

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• SKU: ELSPDEH100341-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PDEH100341-100
• Package Unit: 100 µg
• Quantity Unit: STK