Abbreviation: SNAP23
Target Synonym: Synaptosomal-associated protein 23;SNAP23;SNAP-23;Vesicle-membrane fusion protein SNAP-23
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
UNIProt ID: O00161
Background: SNAP23 (Synaptosomal associated protein 23; also Syndet) is a membrane-associated 23?29 kDa member of the SNAP25 family of proteins. It is expressed in multiple cell types, including neutrophils, platelets, mast cells and adipocytes. SNAP23 is involved in vesicle exocytosis. It has been proposed that SNAP23 can associate with both vesicle and target (cell) membranes via a lipid modification. As a v-SNARE, it may interact with syntaxin-6 at the cell membrane. As a t-SNARE, in conjunction with syntaxin-4, it likely interacts with VAMP-2 and -8 on the vesicle membrane. In either case, this approximates two membranes, which subsequently fuse to create a pore.
Sequence: Met 1-Ser 211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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