Target Synonym: Epithin;HAI;Membrane type serine protease 1;MTSP1;Prostamin;PRSS14;Serine protease 14;SNC19;ST14;TADG15;TMPRSS14
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: Q9Y5Y6
Background: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH). ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.
Sequence: Thr 571-Val 855
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.