Abbreviation: IL2
Target Synonym: Aldesleukin;IL 2;IL-2;IL2;IL2;Interleukin 2;Interleukin-2;Involved in regulation of T cell clonal expansion;Lymphokine;OTTHUMP00000164090;POIL2;T Cell Growth Factor;T-cell growth factor;TCGF
Target Species: Mouse
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P04351
Background: IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions,including T cell proliferation,interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
Sequence: Ala21-Gln169
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.