Abbreviation: C1Inh
Target Synonym: Plasma protease C1 inhibitor;C1 Inh;C1Inh;C1 esterase inhibitor;C1-inhibiting factor;Serpin G1;Serping1
Target Species: Rat
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: Q6P734
Background: Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein
Sequence: Met1-Ala504
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.