Abbreviation: IL-4
Target Synonym: Interleukin-4;IL4;B-cell stimulatory factor 1;BSF-1;Binetrakin;Lymphocyte stimulatory factor 1;Pitrakinra
Target Species: Rat
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: P20096
Background: Participates in at least several B-cell activation processes as well as of other cell types.It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
Sequence: Met1-Ser147
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.
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