Application Note: WB: 1:300-1:5000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 105
Form: Liquid
Buffer (with preservative): 0.01M TBS pH 7.4, 1% BSA, 50% glycerol, 0.03% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
Uniprot ID: Q86TH1
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human ADAMTSL2 (522-580)
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: ADAMTS like 2
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