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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. 100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
    100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
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    Sku MEXHY-Y1977-5
    Manufact. SkuHY-Y1977-5
    Packaging Unit5 mL
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  2. 100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
    100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer
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    Sku MEXHY-Y1977-10
    Manufact. SkuHY-Y1977-10
    Packaging Unit10 mL
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  3. MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH, CAS 2626930-84-3
    MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH, CAS 2626930-84-3
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    Sku MEXHY-W731085-1
    Manufact. SkuHY-W731085-1
    Packaging Unit1 mg
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  4. DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
    DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
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    Sku MEXHY-W591408-5
    Manufact. SkuHY-W591408-5
    Packaging Unit5 mg
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  5. DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
    DBCO-Val-Cit-PAB-MMAE, CAS 2768446-73-5
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    Sku MEXHY-W591408-10
    Manufact. SkuHY-W591408-10
    Packaging Unit10 mg
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  6. Ladiratuzumab vedotin, CAS 1629760-29-7
    Ladiratuzumab vedotin, CAS 1629760-29-7
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    Sku MEXHY-P99683-0
    Manufact. SkuHY-P99683-0
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  7. Iladatuzumab vedotin, CAS 1906205-77-3
    Iladatuzumab vedotin, CAS 1906205-77-3
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    Sku MEXHY-P99657-0
    Manufact. SkuHY-P99657-0
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  8. DOTA-cyclo(RGDfK), CAS 909024-55-1
    DOTA-cyclo(RGDfK), CAS 909024-55-1
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    Sku MEXHY-P10732-0
    Manufact. SkuHY-P10732-0
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  9. DOTA-NAPamide, CAS 935886-72-9
    DOTA-NAPamide, CAS 935886-72-9
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    Sku MEXHY-P10731-0
    Manufact. SkuHY-P10731-0
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  10. DOTA-Lanreotide, CAS 213187-44-1
    DOTA-Lanreotide, CAS 213187-44-1
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    Sku MEXHY-P10730-0
    Manufact. SkuHY-P10730-0
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