1-Boc-azetidine-3-yl-methanol, CAS 142253-56-3

Product Description: 1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Applications: Cancer-programmed cell death

Formula: C9H17NO3

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

CAS Number: 142253-56-3

Molecular Weight: 187.24

Compound Purity: 99.92

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-40152-500
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-40152-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK