Ald-Ph-PEG4-bis-PEG3-methyltetrazine

Ald-Ph-PEG4-bis-PEG3-methyltetrazine
SKU
MEXHY-130974-0
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Manufacturer
MedChemExpress

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Product Description: Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Applications: Cancer-programmed cell death

Formula: C66H94N14O19

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 1387.53

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
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SKU MEXHY-130974-0
Manufacturer MedChemExpress
Manufacturer SKU HY-130974-0
Green Labware No
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