Amidate-VC-PAB-MMAF, CAS 2202782-90-7

Product Description: Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1].

Applications: Cancer-programmed cell death

Formula: C69H102N11O16P

References: [1]Nareshkumar Jain, et al. Current ADC Linker Chemistry. Pharm Res. 2015 Nov;32(11):3526-40.

CAS Number: 2202782-90-7

Molecular Weight: 1372.59

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-145951-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145951-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK