Amino-PEG4-bis-PEG3-N3

Amino-PEG4-bis-PEG3-N3
SKU
MEXHY-136090-0
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MedChemExpress

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Product Description: Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C36H70N10O15

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 883.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
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SKU MEXHY-136090-0
Manufacturer MedChemExpress
Manufacturer SKU HY-136090-0
Green Labware No
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