Azide-C2-SS-C2-biotin, CAS 1620523-64-9

Product Description: Azide-C2-SS-C2-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-C2-SS-C2-biotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C14H24N6O2S3

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 1620523-64-9

Molecular Weight: 404.57

Compound Purity: 98.79

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-140127-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-140127-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK