Azido-PEG1-Val-Cit-PABC-PNP

Product Description: Azido-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C30H39N9O10

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 685.68

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-136105-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136105-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK