Azido-PEG7-amine, CAS 1333154-77-0

Product Description: Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG7-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C16H34N4O7

References: [1]Kevin W. Gillman, et al. Macrocyclic peptides useful as immunomodulators. WO2016077518A1.

CAS Number: 1333154-77-0

Molecular Weight: 394.46

Compound Purity: 95.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-130324-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130324-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK