Azido-PEG9-acid, CAS 1670249-37-2

Product Description: Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: COVID-19-immunoregulation

Formula: C21H41N3O11

References: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

CAS Number: 1670249-37-2

Molecular Weight: 511.56

Compound Purity: 96.0

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-130475-500
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130475-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK