β-Amanitin, CAS 21150-22-1

Product Description: β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs)[1][2].

Applications: Cancer-programmed cell death

Formula: C39H53N9O15S

References: [1]Kaya E, et al. Evaluation and comparison of alpha- and beta-amanitin toxicity on MCF-7 cell line. Turk J Med Sci. 2014;44(5):728-32./[2]Lutz C, et al. Alpha- and Beta-Amanitin Total Synthesis. Angew Chem Int Ed Engl. 2020 Feb 24.

CAS Number: 21150-22-1

Molecular Weight: 919.95

Compound Purity: 96.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;DNA/RNA Synthesis

• SKU: MEXHY-125586-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125586-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK