Biotin-PEG1-azide, CAS 1204085-48-2

Product Description: Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Biotin-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C14H24N6O3S

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 1204085-48-2

Molecular Weight: 356.44

Compound Purity: 99.88

Research Area: Cancer

Solubility: H2O : 25 mg/mL (ultrasonic)

Target: ADC Linker

• SKU: MEXHY-W096133-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W096133-10
• Package Unit: 10 mg
• Quantity Unit: STK