Product Description: Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2].
Applications: Cancer-programmed cell death
Formula: C16H31NO8
References: [1]Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2018114798A1./[2]Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.