DBCO-PEG4-GGFG-Dxd, CAS 2694856-51-2

Product Description: DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG[1]. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C72H79FN10O17

References: [1]Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262.

CAS Number: 2694856-51-2

Molecular Weight: 1375.45

Compound Purity: 99.34

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-134723-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-134723-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK